PlasmaCell CAD: A computer-aided diagnosis software tool for plasma cell recognition and characterization in microscopic images Rasoul Kasbgara,c,1, Alireza Varda,b,1,* aDepartment of Bioelectrics and Biomedical Engineering, School of Advanced Technologies in Medicine, Isfahan University of Medical Sciences, Isfahan 81746, IranbMedical Image & Signal Processing Research Center, School of Advanced Technologies in Medicine, Isfahan University of Medical Sciences, Isfahan 81746, IrancStudent Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran *Corresponding author at: Department of Bioelectrics and Biomedical Engineering, School of Advanced Technologies in Medicine, Isfahan University of Medical Sciences, Isfahan 81746, Iran. E-mail addresses: vard@amt.mui.ac.ir, alivard@gmail.com(A. Vard). 1These Authors contributed equally to this work. https://doi.org/10.1016/j.ijmedinf.2025.105869 Received 3 October 2024; Received in revised form 29 January 2025; Accepted 5 March 2025 Availableonline6March20251386-5056/©2025ElsevierB.V.Allrightsarereserved,includingthosefortextanddatamining,AItraining,andsimilartechnologies.